Browse our latest Stem Cells and Regenerative Medicine articles

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    1. Stem Cells and Regenerative Medicine

    A versatile high-throughput assay based on 3D ring-shaped cardiac tissues generated from human induced pluripotent stem cell-derived cardiomyocytes

    Magali Seguret, Patricia Davidson ... Jean-Sébastien Hulot
    A novel hydrogel-based platform uses a limited number of cells for tissue generation and offers unique advantages for high-throughput cardiac tissue culture.
    1. Stem Cells and Regenerative Medicine

    Context-dependent modification of PFKFB3 in hematopoietic stem cells promotes anaerobic glycolysis and ensures stress hematopoiesis

    Shintaro Watanuki, Hiroshi Kobayashi ... Keiyo Takubo
    Isotope tracing, mathematical modeling, and single-cell ATP analysis reveal changes in blood cell metabolism under various conditions, showing stressed hematopoietic stem cells support hematopoiesis through glycolytic ATP production via PFKFB3.
    1. Stem Cells and Regenerative Medicine

    Switching of RNA splicing regulators in immature neuroblasts: a key step in adult neurogenesis

    Corentin Bernou, Marc-André Mouthon ... François D. Boussin
    1. Stem Cells and Regenerative Medicine

    Ex vivo expansion potential of murine hematopoietic stem cells is a rare property only partially predicted by phenotype

    Qinyu Zhang, Rasmus Olofzon ... David Bryder
    Application of a polyvinyl alcohol-based culture system reveals extensive differentiation but simultaneous robust murine hematopoietic stem cell (HSC) expansion, which are characterized by phenotypic, functional, and molecular properties shared with freshly isolated bone marrow HSCs.