Biochemistry and Chemical Biology

Biochemistry and Chemical Biology

eLife reviews research that gives new insights into biological molecules or uses chemical approaches to illuminate complex biological processes. Learn more about what we review and sign up for the latest research.
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Latest articles

    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    The nanoscale organization of the Nipah virus fusion protein informs new membrane fusion mechanisms

    Qian Wang, Jinxin Liu ... Qian Liu
    1. Biochemistry and Chemical Biology

    ProteasomeID: quantitative mapping of proteasome interactomes and substrates for in vitro and in vivo studies

    Aleksandar Bartolome, Julia C. Heiby ... Alessandro Ori
    1. Biochemistry and Chemical Biology
    2. Plant Biology

    Allosteric activation of the co-receptor BAK1 by the EFR receptor kinase initiates immune signaling

    Henning Mühlenbeck, Yuko Tsutsui ... Cyril Zipfel
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Endogenous oligomer formation underlies DVL2 condensates and promotes Wnt/β-catenin signaling

    Senem Ntourmas, Martin Sachs ... Dominic B. Bernkopf
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Deciphering the actin structure-dependent preferential cooperative binding of cofilin

    Kien Xuan Ngo, Huong T Vu ... Taro Q.P. Uyeda
    1. Biochemistry and Chemical Biology

    Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by SWR1C

    Alexander S. Baier, Nathan Gioacchini ... Craig L. Peterson
    1. Biochemistry and Chemical Biology
    2. Evolutionary Biology

    A mitochondrial carrier transports glycolytic intermediates to link cytosolic and mitochondrial glycolysis in the human gut parasite Blastocystis

    Eva Pyrihová, Martin S. King ... Edmund R.S. Kunji
    1. Biochemistry and Chemical Biology

    A multi-hierarchical approach reveals d-serine as a hidden substrate of sodium-coupled monocarboxylate transporters

    Pattama Wiriyasermkul, Satomi Moriyama ... Shushi Nagamori
    An unbiased approach unveils a non-canonical substrate of the known transporters, highlighting the mechanism behind the use of D-serine as a kidney biomarker.
    1. Biochemistry and Chemical Biology

    Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms

    George N. Bendzunas, Dominic P Byrne ... Natarajan Kannan
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4

    Sandeep K. Ravala, Sendi Rafael Adame-Garcia ... John J. G. Tesmer
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Highlights

    1. Structural Biology and Molecular Biophysics
    2. Cell Biology
    3. Biochemistry and Chemical Biology

    Allosteric Regulation of Kinase Activity – call for papers

    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology
    3. Genetics and Genomics

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    1. Biochemistry and Chemical Biology

    A molecular dual carriageway

    William J Allen, Ian Collinson

Senior editors

  1. Amy H Andreotti
    Iowa State University, United States
  2. Qiang Cui
    Boston University, United States
  3. David Ron
    Cambridge University, United Kingdom
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